In one of the exciting matchups on the ACC college basketball slate on Saturday, the Eastern Kentucky Colonels and Louisville Cardinals square off at KFC Yum! Center — continue reading for our ATS predictions.

Catch tons of live college basketball, plus original programming, with ESPN+ or the Disney Bundle.

ACC Picks ATS Today

Place your bets on any men’s college basketball matchup at BetMGM. Sign up today using our link.

Pick: Eastern Kentucky +19.5 vs. Louisville

• Matchup: Eastern Kentucky Colonels at Louisville Cardinals
• Projected Favorite & Spread: Louisville by 14.4 points (Bet on BetMGM)
• Spread: Louisville -19.5
• Time: 12:00 PM ET
• Date: December 28
• TV Channel: The CW
• Live Stream: Watch this game on Fubo (Regional restrictions may apply)

Bet on this or any men’s college basketball matchup at BetMGM.

Pick: Bucknell +13 vs. Syracuse

• Matchup: Bucknell Bison at Syracuse Orange
• Projected Favorite & Spread: Syracuse by 11.2 points (Bet on BetMGM)
• Spread: Syracuse -13
• Time: 2:00 PM ET
• Date: December 28
• TV Channel: The CW
• Live Stream: Watch this game on Fubo (Regional restrictions may apply)

Bet on this or any men’s college basketball matchup at BetMGM.

Pick: Alabama A&M +22 vs. Georgia Tech

• Matchup: Alabama A&M Bulldogs at Georgia Tech Yellow Jackets
• Projected Favorite & Spread: Georgia Tech by 20.5 points (Bet on BetMGM)
• Spread: Georgia Tech -22
• Time: 2:00 PM ET
• Date: December 28
• TV Channel: ACC Network
• Live Stream: Watch this game on Fubo (Regional restrictions may apply)

Bet on this or any men’s college basketball matchup at BetMGM.

Pick: Fairleigh Dickinson +14.5 vs. Boston College

• Matchup: Fairleigh Dickinson Knights at Boston College Eagles
• Projected Favorite & Spread: Boston College by 11.2 points (Bet on BetMGM)
• Spread: Boston College -14.5
• Time: 4:00 PM ET
• Date: December 28
• TV Channel: ACC Network
• Live Stream: Watch this game on Fubo (Regional restrictions may apply)

Bet on this or any men’s college basketball matchup at BetMGM.

Not all offers available in all states, please visit BetMGM for the latest promotions for your area. Must be 21+ to gamble, please wager responsibly. If you or someone you know has a gambling problem, contact 1-800-GAMBLER.